With all eyes from acro s the footballing world falling on Englands top-flight over the weekend, the 2022/23 Premier League campaign got underway with plenty of major talking points.While defending champions Manchester City and Tottenham might have opened the New Year with a pair of routine victories, others failed to hit the ground running.Watching both Manchester United and Liverpool drop shock points in their opening showdowns, there could Jacob Evans III Jersey be some early-season nerves kicking in behind the scenes.With the first weekend of the 2022/23 campaign now behind us, we have taken a look at a few of the big losers of the Premier Leagues return.Manchester UnitedEnjoying what was an eye-catching pre-season run while on their tour of Australia this summer, Manchester United opened Sundays showdown against Brighton looking to lay down an early marker.However, while Erik ten Hag might have been desperate for his new squad to come flying out the traps on his first competitive contest in the Old Trafford dugout, it was a nightmare start for the Red Devils.Eventually slumping to a 2-1 lo s against the Seagulls on home soil and met by a chorus of boos at both the half-time and full-time whistle, there appear to still be some glaring i sues in Manchester.Heavily outplayed by Brighton from the opening whistle and with Sir Alex Ferguson watching on Maurice Harkless Jersey from the stands, ten Hag was hugely critical of his sides dreadful start.Largely selecting the same starting XI that so publically struggled last season, Brightons victory in Manchester was their first ever win at Old Trafford.Still dealing with the ongoing saga regarding Cristiano Ronaldo and a potential departure this summer, the mood in ten Hags camp will already be worryingly fragile.LiverpoolAlthough Liverpool might have managed to go one step further than Manchester United in getting a point on the board, Jurgen Klopps men will know that they mi sed out on a real chance.After mi sing out on reclaiming the Premier League title last season ASAP Ferg Jersey by just a single point, the one-time Boru sia Dortmund bo s saw his side get off to a stuttering start on Saturday lunchtime.Making the trip to top-flight returners Fulham and tipped as a landslide pick by many, Liverpool eventually had to settle for a 2-2 draw in west London.Despite lifting the Community Shield thanks to a 3-1 victory against Manchester City last month, Klopps side would have preferred to lay down an early marker away from Anfield.While fans around Merseyside might have been glad to see both Darwin Nunez and Mohamed Salah open their accounts at Craven Cottage, Thiagos suspected hamstring injury will be a major worry.Limping off after 50 minutes, Klopp confirmed that he is concerned that the Spanish midfielder could face a lengthy stint on the sidelines.Aston VillaAfter having to settle for a disappointing 14th-place finish last season, Aston Villa have been vocal about their desire to potentially mount a European New York Knicks T-Shirts charge this time around.However, although Steven Gerrards side might have enjoyed their own impre sive pre-season run over the summer, the former Rangers bo s will now have some growing pre sure on his shoulders.Despite welcoming Philippe Coutinho back to Villa Park on a permeant basis and also adding the likes of Diego Carlos and Boubacar Kamara, the Clarets put in a worrying display over the weekend.Despite smelling the chance to make an early statement as they made the trip to Premier League returners Bournemouth, Villa were eventually hit with a shock 2-0 lo s.Mustering just a pair of shots on target and offering little in the final third, Gerrard also found himself on the end of some rather scathing criticism.Signing off the 2021/22 campaign by collecting just a pair Obi Toppin Jersey of wins from their final 11 Premier League appearances, Saturdays display would have undone all Villas hard work over the summer.